Key components

  • NanoWizard® AFM system consisting of AFM head, controller and software
  • BioMAT™ base with built-in optics
  • Upright optical microscope with modified sample stage
  • JPK shuttle stage with clamp fixation and XY coarse adjustment

BioMAT™ base

  • Solid mechanical base for highest resolution AFM operation
  • Integrated optical system for position calibration with focusing and illumination
  • Precision positioning for the AFM alignment

Shuttle stage

  • Easy to handle and to carry
  • 10 mm manual travel range in XY
  • < 5 μm (typically 3 μm) repeatability of AFM and optical microscope co-localization
  • Fully liquid proof design
  • Precision sample clamp for a large variety of samples
  • Shuttle stage with integrated Petri dish heater optional

Upright optical microscope

  • A large variety of research grade upright microscopes can be used (e.g. Zeiss AxioImager series, Axioscope.A1, Axioskop 2 mot.; Olympus BX51/BX61, BX53, BXFM, OLS 4100 LEXT, Nikon Eclipse LV150/150A, Eclipse E600; Leica DM 4000/5000..)
  • No restrictions on imaging modes (brightfield, DIC, fluorescence, also FCS, FRET, FLIM, Raman, etc.)
  • Full compatibility with confocal laser scanning microscopes (CLSM)
  • Use of water dipping objectives for measurements in fluid
  • Optical microscope can be located independent from the AFM system, sample transfer is done by shuttle stage

AFM specifications

  • High performance NanoWizard® AFM system
  • Qi™ mode for easy to use quantitative imaging (see QI™ brochure)
  • DirectOverlay™ feature for direct correlation of AFM and optical data

View all NanoWizard AFM specifications


Fields of application

Non-transparent samples
  • Biochips such as DNA or protein chips
  • Cell-electronics interfaces, cell chips or patterned substrates for cell growth
  • Tissue engineering and implants
  • Bacterial or yeast studies on non-transparent substrates like metals or plastics biofouling
  • Bionics studies
  • Plant biology
  • Nanostructured surfaces from PDMS or other imprints
  • Micromechanical (MEMS/NEMS) systems
  • Nanoparticles, powders, foams, paintings or thin films
  • Organic coatings on metals, plastics or silicone substrates for biocompatible surfaces
  • Nano-electrical measurements of electrical devices