ForceRobot®. The New Era in Force Spectroscopy.

Force spectroscopy is a single molecule technique
that allows the real-time study of molecular interactions on the nano scale. Originating from the broad field of Atomic Force Microscopy (AFM), force spectroscopy provides the necessary sensitivity to characterize biomolecular interactions such as the unfolding forces of single proteins or forces of a single chemical bond.

Automated force spectroscopy

Folding/unfolding dynamics
Binding site localization
Inter- and intramolecular interactions
ForceRobot

A label-free single molecule technique

Force spectroscopy provides information on molecular properties without the need for chemical labeling. This information is relevant for the study of:

Intermolecular interaction examples

Characterization of receptor-ligand, antibody-antigen,
or DNA/aptamer-protein interactions in biophysics, biochemistry, and molecular cell biology
Molecular adhesion studies in surface chemistry
and polymer science

Intramolecular interaction examples

DNA melting, polymer stretching, protein unfolding,
and polysaccharide elasticity in molecular medicine,
pharmacology, bionics and food technology

 

 

ForceRobot head
 ForceRobot® head

ForceRobot PDF file
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Applications