JPK Service Center
Latest News
August 26, 2008
JPK release Petri dish heater for live cell imaging experimentsAugust 26, 2008
JPK announces hiring of Singapore managerJuly 10, 2008
JPK announce the next NanoBioVIEWS™ International Meeting: a two-day symposium on the application of SPM for Life SciencesJune 4, 2008
Leading scientists meet at the NanoBioVIEWS™ first International Symposium on Optical Tweezers in Life Sciences
- Tutorials
- Scientific Papers
- More Literature
- Links
This section provides an introduction to the different techniques.
Bio Atomic Force Microscopy
The atomic force microscope (AFM) is one of the family of scanning probe microscopes, and is widely used in biological applications. The AFM uses a flexible cantilever to measure the force between the tip and the sample, for high resolution imaging, force measurements and manipulation.
- AFM tutorial: Here you can find extensive information about the basic principles and methods of scanning probe microscopy:
- Pflugers Arch - Eur J Physiol 456:29-49 (2008): T. Ludwig, R. Kirmse, K. Poole, U.S. Schwarz, "Probing cellular microenvironments and tissue remodeling by atomic force microscopy " - This paper provides a good review of AFM applied to cell imaging, mechanics and adhesion.
Automated Force Spectroscopy
Force spectroscopy is a single molecule technique that allows the real-time study of molecular interactions on the nanoscale. Originating from the broad field of Atomic Force Microscopy, force spectroscopy provides the necessary sensitivity to characterize biomolecular interactions such as the unfolding forces of single proteins or forces of a single chemical bond.
- Nanotechnology (2008), 384020: J. Struckmeier, R. Wahl, M. Lueschner, J. Nunes, H. Janovjak, J. Helenius, U. Geisler, G. Hofmann, T. Jaehnke and D.J. Mueller, "Fully automated single-molecule force spectroscopy for screening applications" - This paper describes the particular technical developments for automated force spectroscopy:
- JPK ForceRobot® AppReport: This report describes the application to titin unfolding.
Cellular Adhesion / Cytomechanics
The innovative CellHesion® methodology opens up new paths for the study of cellular interactions. The CellHesion is an instrument for force measurement, based on AFM technology, and specialized for measuring cell adhesion and cell mechanics.
- CellHesion® App- and TechReports: These reports provide a good introduction to the technique and applications
- Sci. STKE 2007, pl5 (2007): C.M. Franz, A. Taubenberger, P.-H. Puech, D.J. Müller, "Studying integrin-mediated cell adhesion at the single-molecule level using AFM force spectroscopy" - This Science Signal Transduction and Knowledge Environment paper describes the experimental protocol for a typical CellHesion® experiment.
Optical tweezers
As the name suggests, optical tweezers are a means to manipulate and measure objects with light. With the NanoTracker™, the user can trap and track particles from several µm down to 30nm with the ability to control, manipulate and observe samples from vesicles to whole cells in real time with nanometer precision.
- JPK NanoTracker TechReport: This report describes the technical basis for quantitative force measurements using optical tweezers.
AFM - Cell imaging and interactions, invited review
- Pflugers Arch - Eur J Physiol 456:29-49 (2008) T. Ludwig, R. Kirmse, K. Poole, U.S. Schwarz, "Probing cellular microenvironments and tissue remodeling by atomic force microscopy "
AFM - Cells and cell structures
- J. Mol. Biol. 372(3): 594-607(2007) J. Friedrichs, A. Taubenberger, C.M. Franz, D.J. Müller, "Cellular remodelling of individual collagen fibrils visualized by time-lapse AFM"
- Exp. Dermatol. 16: 1007-1015 (2007) A. Reich, B. Lehmann, M. Meurer, D.J. Müller, "Structural alterations provoked by narrow-band ultraviolet B in immortalized keratinocytes: assessment by atomic force microscopy"
- J. Cell Sci. 118: 5315-5323 (2005) C.M. Franz, D.J. Müller "Analyzing focal adhesion structure by atomic force microscopy"
- FEBS Letters 565: 53-58 (2004) K. Poole, D. Meder, K. Simons, D. Müller, "The effect of raft lipid depletion on microvilli formation in MDCK cells, visualized by atomic force microscopy"
- FEBS Letters 579: 2001-2008 (2005) A. Sharma, K.I. Anderson, D.J. Müller, "Actin microridges characterized by laser scanning confocal and atomic force microscopy"
- J. Mol. Biol. 349: 380-386 (2005) K. Poole, K. Khairy, J. Friedrichs, C. Franz, D.A. Cisneros, J. Howard, D. Mueller, "Molecular-scale topographic cues induce the orientation and directional movement of fibroblasts on two-dimensional collagen surfaces"
- Pflugers Arch - Eur J Physiol 456:83-93 (2008) S. Wegmann, M. Miesbauer, K.F. Winklhofer, J. Tatzelt, D.J. Müller, "Observing fibrillar assemblies on scrapie-infected cells"
- Jap. J. App. Phys. 45 (3B): 2341-2344 (2006) J.M. Burns, A. Cuschieri, P.A. Campbell "Optimisation of fixation period on biological cells via time-lapse elasticity mapping"
- Nature Physics 1, 107 - 110 (2005) P. Prentice, A. Cuschieri, K. Dholakia, M. Prausnitz, P. Campbell, "Membrane disruption by optically controlled microbubble cavitation"
- Exp. Dermatol. 15: 387-391 (2006) C. Gorzelanny, T. Görge, E.-M. Schnäker, K. Thomas, T.A. Luger, S.W. Schneider, "Atomic force microscopy as an innovative tool for nanoanalysis of native stratum corneum"
AFM - Single molecules, protein, lipids
- Biophys. J. 90: 4500-4508 (2006) S. Chiantia, N. Kahya, J. Ries, P. Schwille, "Effects of ceramide on liquid-ordered domains investigated by simultaneous AFM and FCS",
- ChemPhysChem 7: 2409-2418 (2006) S. Chiantia, N. Kahya, J. Ries, P. Schwille "Combined AFM and two-focus SFCS study of raft-exhibiting model membranes"
- Langmuir 21 (14): 6317-6323 (2005) S. Chiantia, N. Kahya, P. Schwille, "Dehydration damage of domain-exhibiting supported bilayers: an AFM study on the protective effects of disaccharides and other stabilizing substances"
- Langmuir 23(14):7659-7665 (2007) S. Chiantia, N. Kahya and P. Schwille, "Raft domain reorganization driven by short- and long-chain ceramide: a combined AFM and FCS study"
- Langmuir 23: 8135-8141 (2007) M.H. Jensen, E.J. Morris, A.C. Simonsen, "Domain shapes, coarsening, and random patterns in ternary membranes",
- J. Mol. Biol. 376: 932-937 (2008) E. Canetta, S.H. Kim, N.O. Kalinina, J. Shaw, A.K. Adya, T. Gillespie, J.W.S. Brown, M. Taliansky "A plant virus movement protein forms ringlike complexes with the major nucleolar protein, fibrillarin, in vitro"
- ChemBioChem 7: 106-115 (2006) K. Kastl, M. Menke, E. L üthgens, S. Faiß, V. Gerke, A. Janshoff, C. Steinem, "Partially reversible adsorption of annexin A1 on POPC/POPS bilayers investigated by QCM measurements, SFM, and DMC simulations"
- Biochemistry 44 (46): 15296-15303 (2005) M. Menke, V. Gerke, C. Steinem "Phosphatidylserine membrane domain clustering induced by annexin A2/S100A10 heterotetramer"
- ChemBioChem 5: 1003-1006 (2004) M. Menke, M. Ross, V. Gerke, C. Steinem, "The molecular arrangement of membrane-bound annexin A2-S100A10 tetramer as revealed by scanning force microscopy"
- Langmuir 22 (18): 7454-7457 (2006) B. Windschiegl, C. Steinem, "Influence of alpha-hydroxylation of glycolipids on domain formation in lipid monolayers"
- Ultramicroscopy 106: 687-694 (2006) Z. Leonenko, E. Finot, V. Vassiliev, M. Amrein, "Effect of cholesterol on the physical properties of pulmonary surfactant films: Atomic force measurements study"
- Langmuir 22: 10135-10139 (2006) Z. Leonenko, M. Rodenstein, J. Döhner, L.M. Eng, M. Amrein, "The electrical surface potential of pulmonary surfactant"
- Biophys. J. 93: 674-683 (2007) Z. Leonenko, S. Gill, S. Baoukina, L. Monticelli, J. Doehner, L. Gunasekara, F. Felderer, M. Rodenstein, L.M. Eng, M. Amrein, "An elevated level of cholesterol impairs self-assembly of pulmonary surfactant into a functional film"
- Thrombosis and Haemostasis 97: 514-526 (2007) A. Barg, R. Ossig, T. Goerge, M. F. Schneider, H. Schiller, H. Oberleithner, S. W. Schneider, "Soluble plasma-derived von-Willebrand-factor assembles to a haemostatically active filamentous network"
AFM - Chromosome manipulation
- Nanotechnology 17: 1391-1396 (2006) K. Tsukamoto, S. Kuwazaki, K. Yamamoto, T. Ohtani, S. Sugiyama, "Dissection and high-yield recovery of nanometre-scale chromosome fragments using an atomic-force microscope"
- Jap. J. Appl. Phys. 45: 2305-2309 (2006) S. Sugiyama, T. Yoshino, K. Tsukamoto, M. Sasou, S. Kuwazaki, H. Takahashi, Y. Suetsugu, J. Narukawa, K. Yamamoto, T. Ohtani, "Application of scanning probe microscopy to genetic analysis"
- Jap. J. Appl. Phys. 45, 2337-2340 (2006) K. Tsukamoto, S. Kuwazaki, K. Yamamoto, M. Shichiri, T. Yoshino, T. Ohtani, S. Sugiyama, "Nanometer-scale dissection of chromosomes by atomic force microscopy combined with heat-denaturing treatment"
AFM - Force spectroscopy / molecular interactions
- J. Mol. Biol. 362: 925-932 (2006) A. Kedrov, C. Ziegler, D.J. Müller "Differentiating ligand and inhibitor interactions of a single antiporter"
- J. Mol. Biol. 375 (5): 1258-1266 (2008) A. Kedrov, M. Appel, H. Baumann, C. Ziegler, D.J. Müller, " Examining the dynamic energy landscape of an antiporter upon inhibitor binding"
- Biophys. J. 93: 103-112 (2007) A.J. García-Sáez, S. Chiantia, J. Salgado, P. Schwille, "Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM"
- J. Biol. Chem. 282: 33537 (2007) A.J. García-Sáez, S. Chiantia, P. Schwille, "Effect of line tension on the lateral organization of lipid membranes"
- J. Am. Chem. Soc. 129 (30): 9349-9355 (2007) Y.J. Jung, B.J. Hong, W. Zhang, S.J.B. Tendler, P.M. Williams, S. Allen and J.W. Park, "Dendron arrays for the force-based detection of DNA hybridization events"
- J. Mol. Recognit. 20: 554-560 (2007) E.Thormann, A.C Simonsen, L.K. Nielsen, O.G. Mouritsen, "Ligand-receptor interactions and membrane structure investigated by AFM and time-resolved fluorescence microscopy"
- Biochemistry 46: 12231-12237 (2007) E. Thormann, J.K. Dreyer, A.C. Simonsen, P.L. Hansen, S. Hansen, U. Holmskov, O.G. Mouritsen, "Dynamic strength of the interaction between lung surfactant protein D (SP-D) and saccharide ligands"
AFM - Polymers, nanosciences, chemistry
- Soft Matter 4: 277-285 (2008) M. Schiek, F. Balzer, K. Al-Shamery, A. Lutzenc, H.-G. Rubahn, "Light-emitting organic nanoaggregates from functionalized p-quaterphenylenes"
- Proc. SPIE 5925:31-38 (2005) F. Balzer, L. Kankate, H. Niehus, H.-G. Rubahn, "Epitaxy vs. dipole assisted growth for organic oligomer nanoaggregates"
- J. Chem. Phys. 128, 084709 (2008) L. Kankate, F. Balzer, H. Niehus, H.-G. Rubahn, "From clusters to fibers: Parameters for discontinuous para-hexaphenylene thin film growth"
- Nanotechnology 17: 984-991 (2006) F. Balzer, L. Kankate, H. Niehus, R. Frese, C. Maibohm, H.-G. Rubahn "Tailoring the growth of p-6P nanofibres using ultrathin Au layers: an organic-metal-dielectric model system"
- Proc. SPIE 6117: 20-27 (2006) F. Balzer, L. Kankate, H. Niehus, H.-G. Rubahn, "Tailoring of organic nanofiber growth for a new type of waveguides"
- J. Am. Chem. Soc. 127: 13082-13083 (2005) target= J.J. Davis, K.S. Coleman, K.L. Busuttil, C.B. Bagshaw, "Spatially resolved Suzuki coupling reaction initiated and controlled using a catalytic AFM probe"
- J. Am. Chem. Soc. 128 (43): 14135-14141 (2006) J.J. Davis, C.B. Bagshaw, K.L. Busuttil, Y. Hanyu, K.S. Coleman, "Spatially controlled Suzuki and Heck catalytic molecular coupling"
- Phys. Chem. Chem. Phys. 9: 2406 - 2412 (2007) M. Valtiner, S. Borodin, G. Grundmeier, "Preparation and characterisation of hydroxide stabilised ZnO(0001)-Zn-OH surfaces"
- J. Am. Chem. Soc., 130 (11): 3664 -3668 (2008) S.W. Schmidt, M.K. Beyer, H. Clausen-Schaumann, "Dynamic strength of the silicon-carbon bond observed over three decades of force-loading rates"
- J. Power Sources, 177 (1): 50-55 (2008) L. Zhou, Y.F. Cheng, M. Amrein, "Fabrication by electrolytic deposition of platinum black electrocatalyst for oxidation of ammonia in alkaline solution"
- Diamond & Related Materials 17: 66-71 (2008) W.-Y. Lee, H. Lin, L. Gu, K.-C. Leou, C.-H. Tsai, "CVD catalytic growth of single-walled carbon nanotubes with a selective diameter distribution"
AFM - Pharmacology/Drug delivery/nanoparticles
- J.Microencapsulation 23: 567-581 (2006) N. Altinbas, C. Fehmer, A. Terheiden, A. Shukla, H. Rehage, C. Mayer, "Alkylcyanoacrylate nanocapsules prepared from mini-emulsions - a comparison with the conventional approach"
- Biomacromolecules 7: 3428-38 (2006) M. Neu, J. Sitterberg, U. Bakowsky, T. Kissel, "Stabilized nanocarriers for plasmids based upon cross-linked poly(ethylene imine)"
- Pharmaceutical Research 23 (1): 184-195 (2006) S. Hariharan, V. Bhardwaj, I. Bala, J. Sitterberg, U. Bakowsky, M.N.V. Ravi Kumar "Design of estradiol loaded PLGA nanoparticulate formulations: a potential oral delivery system for hormone therapy"
- Biomacromolecules 7: 215-223 (2006) R.Y. Kannan, H.J. Salacinski, J. De Groot, I. Clatworthy, L. Bozec, M. Horton, P.E. Butler, A.M. Seifalian, "The antithrombogenic potential of a polyhedral oligomeric silsesquioxane (POSS) nanocomposite"
- Nanotechnology 18: 115710(10pp) (2007) L. Kaufner, R. Cartier, R. Wüstneck, I. Fichtner, S. Pietschmann, H. Bruhn, D. Schütt, A.F. Thünemann, U. Pison, "Poly(ethylene oxide)-block-poly(glutamic acid) coated maghemite nanoparticles: in vitro characterization and in vivo behaviour"
- Journal of Membrane Science 309: 165-174 (2008) Y. Chang, Y.J. Shih, R.C. Ruaan, A. Higuchi, W.Y. Chen, J.Y. Lai, "Preparation of poly(vinylidene fluoride) microfiltration membrane with uniform surface-copolymerized poly(ethylene glycol) methacrylate and improvement of blood compatibility"
- Nanotechnology 19: 075301 (2008) T.M. Blättler, A. Binkert, M. Zimmermann, M. Textor, J. Vörös, E. Reimhult, "From particle self-assembly to functionalized sub-micron protein patterns"
- J. Biotech. 130: 247-252 (2007) V. Saravia, S. Kupcu, M. Nolte, C. Huber, D. Pum, A. Fery, U.B. Sleytr, J.L. Toca-Herrera, "Bacterial protein patterning by micro-contact printing of PLL-g-PEG"
- Nanotechnology 18: 325102 (2007) K.-K. Liu, C.-L. Cheng, C.-C. Chang, J.-I Chao, "Biocompatible and detectable carboxylated nanodiamond on human cell"
AFM - Bionics / Biomechanics / Biotechnology
- PNAS 102 (45): 16293-16296 (2005) G. Huber, H. Mantz, R. Spolenak, K. Mecke, K. Jacobs, S.N. Gorb, E. Arzt "Evidence for capillarity contributions to gecko adhesion from single spatula nanomechanical measurements"
- Biol. Lett. 1: 2-4 (2005) G. Huber, S.N. Gorb, R. Spolenak, E. Arzt "Resolving the nanoscale adhesion of individual gecko spatulae by atomic force microscopy"
- Acta Biomaterialia 3 (4): 607-610 (2007) G. Huber, S.N. Gorb, N. Hosoda, R. Spolenak, E. Arzt, "Influence of surface roughness on gecko adhesion"
- Biophys. J. (2008) L. Kreplak, H. Herrmann, U. Aebi, "Tensile properties of single desmin intermediate filaments"
- Ultramicroscopy 105 (1-4): 79-89 (2005) L. Bozec, J. de Groot, M. Odlyha, B. Nicholls, S. Nesbitt, A. Flanagan, M. Horton "Atomic force microscopy of collagen structure in bone and dentine revealed by osteoclastic resorption"
- J Mater Sci: Mater Med 17:1043-1048 (2006) L. Bozec, M.A. Horton, "Skeletal tissues as nanomaterials"
- Biophys. J. 93:1255-1263 (2007) M.P.E. Wenger, L. Bozec, M.A. Horton, P. Mesquida, "Mechanical properties of collagen fibrils"
- Nanotechnology 19: 035506 (2008) J.F.C. Windmill, A. Zorab, D.J. Bedwell, D. Robert, "Nanomechanical and electrical characterization of a new cellular electret sensor-actuator"
- Biomaterials 29 (2): 247-256 (2008) M.S. Jaeger, K. Uhlig, H. Clausen-Schaumann, C. Duschl, "The structure and functionality of contractile forisome protein aggregates"
AFM - Cell Mechanics / Cell Motility
- Current Biology 18: 91-101 (2008) P. Kunda, A.E. Pelling, T. Liu, B. Baum, "Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis"
- J. Mol. Recognit. 20: 1-9 (2007) A.E. Pelling, F.S. Veraitch, C. Chu, B.M. Nicholls, A.L. Hemsley, C.Mason, M.A. Horton, "Mapping correlated membrane pulsations and fluctuations in human cells"
- PNAS 103: 17759-17764 (2006) Y.-B. Lu, K. Franze, G. Seifert, C. Steinhäuser, F. Kirchhoff, H. Wolburg, J. Guck, P.Janmey, E.-Q. Wei, J. Käs, A. Reichenbach, "Viscoelastic properties of individual glial cells and neurons in the CNS"
- Eur. Biophys. J. 35 (8): 713-719 (2006) C.A. Brunner, A. Ehrlicher, B. Kohlstrunk, D. Knebel, J.A. Käs, M. Goegler, "Cell migration through small gaps",
- Ultramicroscopy 107 (10):.948-953 (2007) Z. Leonenko, E. Finot, M. Amrein, "Adhesive interaction measured between AFM probe and lung epithelial type II cells"
- J.Cell. Mol. Med. 12 (2): 537-552 (2008) D. Docheva, D. Padula, C. Popov, W. Mutschler, H. Clausen-Schaumann, M. Schieker, "Researching into the cellular shape, volume and elasticity of mesenchymal stem cells, osteoblasts and osteosarcoma cells by atomic force microscopy"
AFM - BioMAT
- App. Environ. Microbiology, 74 (2): 410-415 (2008) S. Mangold, K. Harneit, T. Rohwerder, G. Claus, W. Sand "Novel combination of atomic force microscopy and epifluorescence microscopy for visualization of leaching bacteria on pyrite"
- Hydrometallurgy in press (2008) S. Mangold, M. Laxander, K. Harneit, T. Rohwerder, G. Claus, W. Sand "Visualization of Acidithiobacillus ferrooxidans biofilms on pyrite by atomic force and epifluorescence microscopy under various experimental conditions"
AFM - TAO
- J. Raman Spectroscopy 37:311-317 (2006) A. Rasmussen, V. Deckert "Surface- and tip-enhanced Raman scattering of DNA components"
- Proc. SPIE 6093: 242-249 (2006) A. Rasmussen, C. Budich, V. Deckert, "Tip-enhanced Raman scattering (TERS) of a DNA binding compound"
- Chem Phys Chem 7(7): 1428-1430 (2006) U. Neugebauer, P. Rösch, M. Schmitt, J. Popp, C. Julien, A. Rasmussen, C. Budich, V. Deckert, "On the way to nanometer-sized information of the bacterial surface by Tip-Enhanced Raman Spectroscopy"
- Chem Phys Chem 8 (1): 124-137 (2006) U. Neugebauer, P. Rösch, M. Schmitt, J. Popp, C. Julien, A. Rasmussen, C. Budich, V. Deckert, "Towards a detailed understanding of bacterial metabolism - spectroscopic characterization of Staphylococcus Epidermis"
- Nature Nanotechnology 2, 635 - 639 (2007) M. Comellas-Aragone, H. Engelkamp, V.I. Claessen, N.A.J.M. Sommerdijk, A.E. Rowan, P.C.M. Christianen, J.C. Maan, B.J.M. Verduin, J.J.L.M. Cornelissen, R.J.M Nolte, "A virus-based single-enzyme nanoreactor"
- Biopolymers 82: 410-414 (2006) R.J. Owen, C.D. Heyes, D. Knebel, C. Röcker, G.U. Nienhaus, "An integrated instrumental setup for the combination of atomic force microscopy with optical spectroscopy"
CellHesion - Technique
- Ultramicroscopy 106: 637-644 (2006) P.-H. Puech, K. Poole, D. Knebel, D.J. Mueller "A new technical approach to quantify cell-cell adhesion forces by AFM"
- Sci. STKE 2007, pl5 (2007) C.M. Franz, A. Taubenberger, P.-H. Puech, D.J. Muller, "Studying integrin-mediated cell adhesion at the single-molecule level using AFM force spectroscopy"
CellHesion - Developmental biology
- J. Cell Sci. 118: 4199-4206 (2005) P.-H. Puech, A. Taubenberger, F. Ulrich, M. Krieg, D.J. Muller, C.-P. Heisenberg "Measuring cell adhesion forces of primary gastrulating cells from zebrafish using atomic force microscopy"
- Developmental Cell 9: 555-564 (2005) F. Ulrich, M. Krieg, E.-M.Schötz, V. Link, I. Castanon, V. Schnabel, A. Taubenberger, D. Mueller, P.-H. Puech, C.-P. Heisenberg, "Wnt11 Functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin"
CellHesion - Cell adhesion
- Mol. Biol. Cell 18 (5): 1634-1644 (2007) A. Taubenberger, D.A. Cisneros, J. Friedrichs, P.-H. Puech, D.J. Muller, C.M. Franz, "Revealing early steps of {alpha}2beta1 integrin-mediated adhesion to collagen type I by using single-cell force spectroscopy"
- J. Biol. Chem. 282 (40): 29375-29383 (2007) J. Friedrichs, J.M. Torkko, J. Helenius, T.P. Teräväinen, J. Füllekrug, D.J. Müller, K. Simons, A. Manninen, "Contributions of Galectin-3 and -9 to epithelial cell adhesion analysed by single cell force spectroscopy"
- J. Cell Sci. 121: 877-886 (2008) P. Pittet, K. Lee, A.J. Kulik, J.-J. Meister, B. Hinz, "Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds"
- J. Mol. Biol. 377 (4): 1082-1093 (2008) F.A. Fierro, A. Taubenberger, P.-H. Puech, G. Ehninger, M. Bornhauser, D.J. Muller, T. Illmer, "BCR/ABL expression of myeloid progenitors increases ?1-integrin mediated adhesion to stromal cells"
Here you will find books about SPM, Nanotechnology and Soft Matter and Life Science . Of course the list is not complete and it is based on our subjective choices. So, if a book that you would like to recommend is not listed here, you are invited to contact us and make a suggestion.
Books about SPM
- Birdi K. S.: Scanning Probe Microscopes: Applications in Science and Technology CRC Press; February 2003, ISBN: 0849309301
- Bonnell Dawn A. (Ed.): Scanning Probe Microscopy and Spectroscopy: Theory, Techniques and Applications John Wiley & Sons; October 2000, ISBN: 047124824X
- Braga P.C., Ricci D. (Eds.): Atomic force microscopy - Biomedical methods and applications. (Methods in Molecular Biology Vol. 242) Humana Press, Totowa 2004, 394 pages, ISBN: 1-59259-647-9
- Cohen Samuel H., Lightbody Marcia L., (Eds.): Atomic Force Microscopy/ Scanning Tunneling Microscopy 2 Plenum Pub. Corp., March 1997, ISBN: 030645596X
- Cohen Samuel H., Lightbody Marcia L., (Eds.): Atomic Force Microscopy/ Scanning Tunneling Microscopy 3 Plenum Pub. Corp., November 1999, ISBN: 0306462974
- Gai Pratibha L., (Ed.): In-Situ Microscopy in Materials Research: Leading International Research in Electron and Scanning Probe Microscopies Kluwer Academic Publishers, June 1997, 360 pages, ISBN: 0792399897
- Gewi, Colton Richard J., Frommer Jane E., Engler Anderas, Gaub Hermann E., (Eds.): Procedures in Scanning Probe Microscopies John Wiley & Sons, Inc., August 1998, 672 pages, ISBN: 047195912X
- Jena Bhanu P., Horber J. K. Heinrich (eds.): Atomic Force Microscopy in Cell Biology (Methods in Cell Biology) Academic Press 2002, 415 p., ISBN: 0123838517 (Paperback), ISBN: 0125441711 (Hardcover)
- Heitmann Winfried: Das Tunneln von elektromagnetischer Strahlung und von Photonen (Berichte aus der Physik) Shaker Verlag, Herzogenrath 1999, ISBN: 3826561481
- Marti Othmar, Amrein Matthias, (Eds.): STM and SFM in Biology Academic Press, July 1993, ISBN: 0124745008
- Minne S. C., Manalis S. R., Quate Calvin F.: Bringing Scanning Probe Microscopy Up to Speed (Microsystems (Series), 3.) Kluwer Academic Publishers; August 1999; ISBN: 0792384660
- Morris V. J., Gunning, A. P., Kirby, A. R.: Atomic Force Microscopy for Biologists Imperial College Press; October 1999, ISBN: 1860941990
- Niemeyer C.M., Mirkin C.A (Eds): Nanobiotechnology. Concepts, applications and perspectives. Wiley VCH, 2004, 469 pages, ISBN 3-527-30658-7
- Persson Bo N.: Sliding Friction; Physical Principles and Applications, Nano Science and Technology Springer Verlag, Berlin 2000, ISBN: 3540671927
- Rao C.N.R., Müller A., Cheetham A.K (Eds.): The chemistry of nanomaterials. Synthesis, properties and applications Wiley VCH, 2004, 741 pages, ISBN 3-527-30686-2
- Ratner B. D., Tsukruk Vladimir V., (Eds.): Scanning Probe Microscopy of Polymers (ACS Symposium Series, No 694) Am. Chem. Soc.: September 1998, ISBN: 0841235627
- Sakurai Toshio, Watanabe Yousuke: Advances in Scanning Probe Microscopy (Advances in Materials Research 2) Springer Verlag, Berlin 2000, ISBN: 3540667180
- Sarid Dror: Scanning Probe Microscopy with Mathematica John Wiley & Sons, November 1997, ISBN: 0471168181
- Sarid Dror: Scanning Force Microscopy: With Applications to Electric, Magnetic and Atomic Forces (Oxford Series in Optical and Imaging Sciences, No 5) Oxford Univ. Press, August 1994, 263 pages, ISBN: 019509204X
- Wiesendanger Roland: Scanning Probe Microscopy and Spectroscopy - Methods and Applications Cambridge University Press 1994, ISBN: 0521418100
- Wiesendanger Roland, Güntherodt H.-J. (Eds.): Scanning Tunneling Microscopy III: Theory of STM and Related Scanning Probe Methods (Springer Series in Surface Sciences, No 29) Springer Verlag, Paperback 2nd edition (May 1997), ISBN: 3540608249
- Wiesendanger Roland (Ed.): Scanning Probe Microscopy: Analytical Methods, Series in "NanoScience and Technology" Springer Verlag, March 1998, ISBN: 3540638156
Books about Nanotechnology
- Ando, T.; Arakawa, Y.; Furuya, K.; Komiyama, S.; Nakashima, H., (Eds.): Mesoscopic Physics and Electronics, Springer Verlag, 1998; Series in "NanoScience and Technology" - Series Editors: K. von Klitzing, R. Wiesendanger, ISBN: 3-540-63587-4
- Avouris Phaedon: Atomic and Nanometer-Scale Modification of Materials: Fundamentals and Applications -Kluwer Academic Publishers, NATO ASI Series 1993.
- Ball Philip: Designing the molecular world (Chemistry at the frontier) -Princeton University Press, New Jersey 1994, ISBN: 0691000581
- Bard Allen J.: Integrated Chemical Systems : A Chemical Approach to Nanotechnology (The George Fisher Baker Non-Resident Lectureship in Chemistry at Cornell Univers.) - John Wiley & Sons 1994, ISBN: 0471007331
- Brundle C. Richard: Encyclopedia of Materials Characterization: Surfaces, Interfaces, Thin Films (Materials Characterization Series) - Butterworth-Heinemann 1992, ISBN: 0750691689
- Crandall B.C., James Lewis: Nanotechnology: Research and Perspectives. Papers from the First Foresight Conference on Nanotechnology, Cambridge - MIT Press Cambridge1992, ISBN: 0262031957
- Darling David: Beyond 2000: Micromachines and Nanotechnology: The Amazing New World of the Ultrasmall - Dillon Pr. 1995, ISBN: 0382249534
- Drexler K. Eric, Chris Petersen, Gayle Pergamit: Unbounding the Future: The Nanotechnology Revolution - New York, Quill 1993. ISBN: 0688125735
- Drexler K. Eric: Engines of Creation - Anchor 1987, ISBN: 0385199732
- Drexler K. Eric: Nanosystems: Molecular Machinery, Manufacturing and Computation - New York, John Wiley and Sons 1992, ISBN: 0471575186
- Endo M. (Ed): Carbon Nanotubes - Pergamon Press Inc 1997, 183 p., ISBN: 0080426824
- Fabbrizzi Luigi, Poggi Antonio (Eds.): Chemistry at the Beginning of the Third Millenium: Molecular Design, Supramolecules, Nanotechnology and Beyond - Springer Verlag Berlin 2000, ISBN: 3540674608
- Göpel W., Hesse J., Zemel J. N.: Sensors: Micro- and Nanosensor Technology/ Trends in Sensor Markets - VCH Verlagsgesellschaft Weinheim 1995.
- Göpel W., Ziegler Ch.: Nanostructures based on molecular materials - VCH Verlagsgesellschaft Weinheim 1992.
- Hoch Harvey C.: Nanofabrication and Biosystems : Integrating Materials Science, Engineering, and Biology - Cambridge University Pr. 1996, ISBN: 0521462649
- Hölzle, Rainer: Physik der Nanostrukturen FZ Jülich: Materie und Material Bd.1, 1998 - ISBN: 3-89336-217-7
- Hubbard Arthur T.: The Handbook of Surface Imaging and Visualization - CRC Pr. 1995, ISBN: 0849389119
- Imry Yoseph: Introduction to Mesoscopic Physics (Mesoscopic Physics and Nanotechnology) - Oxford Univ. Pr. 1997, ISBN: 0195101677
- Koruga Djuro: Fullerene C60: History, Physics, Nanobiology, Nanotechnology - Elsevier Science Ltd. 1993, ISBN: 0444898336
- Kuzmany Hans, Fink Jörg et.al. (Eds.): Electronic Properties of Novel Materials: Science and Technology of Molecular Nanostructures - AIP Press USA, Woodbury, 1999, ISBN: 1563969009
- Lorenz Wolfgang, Plieth Waldfried (Eds.): In Situ Local Probe Techniques at Electrochemical Interfaces - Wiley-VCH Verlag, Weinheim 1998, ISBN: 3527295208
- Smith S.T., Chetwynd D.G.: Foundations of Ultraprecision Mechanism Design (Developments in Nanotechnology, Vol 2) - Harwood Academic Pub. 1994, ISBN: 2884490019
- Timp Gregory L. (Ed.): Nanotechnology - AIP Press, Springer Verlag, New York 1999, ISBN: 0387983341
- Whang, Zhong L. (Ed.): Characterization of Nanophase Materials. - Wiley VCH, Weinheim 1999, ISBN: 3527298371
- Welland M. E., Gimzewski J. K.: Ultimate Limits of Fabrication and Measurement. - Kluwer Academic Publishers, NATO ASI Series 1995, ISBN: 079233504X
Books about Soft Matter and Life Science
- Arai Toshihiro, Mihama Kazuhiro (Eds.): Mesoscopic Materials and Clusters: Their Physical and Chemical Properties -Springer Verlag, Berlin, ISBN: 3540648844
- Bast Eckehard: Mikrobiologische Methoden:Eine Einführung in grundlegende Arbeitstechniken - Spektrum Akademischer Verlag, Heidelberg 1999, ISBN: 3827407869
- Baur Herbert: Thermophysics of Polymers I. Theory - Springer Verlag Berlin, 1999, ISBN: 3540650466
- Butt Hans-Jürgen, Graf Karlheinz, Kappl Michael (eds.): Physics and Chemistry of Interfaces -Wiley-VCH, 2003, 373 p., ISBN: 3527404139
- Eklund Peter C., RAO Apparao M. (Eds.): Fullerene Polymers and Fulleren Polymer Composites (Springer Series Materials Science 37) -Springer Verlag, Berlin 2000, ISBN: 3540648941
- Glaser Roland: Biophysics -Springer Verlag, Berlin 2001, ISBN: 3540670882
- Glick Bernand R., Pasternak Jack J.: Molekulare Biologie - Spektrum Akademischer Verlag, Heidelberg 1995, ISBN: 3860253786
- Israelachvili Jacob N.: Intermolecular & surface forces -Academic press 1992, 2nd ed., 450 p., ISBN: 0123751810
- Manz Andreas, Becker Holger (EDs.): Microsystem Technology in Chemistry and Life Science -Springer Verlag, Berlin 1999, ISBN: 3540655557
- Silver Frederick H., Christiansen David: Biomaterials in Science and Biocompatibility -Springer Verlag, New York 1999, ISBN: 0387987118
- Sonnleitner B.: Bioanalysis; Bioanalysis and Biosensors for Bioprocess Monitoring (Advances Biochem. Engineering, Vol. 66) -Springer Verlag, Berlin 2000, ISBN: 3540660526
- Winter Roland, Noll Frank: Methoden der Biophysikalischen Chemie (Teubner Studienbücher) -Teubner Verlag, Wiesbaden 1998, ISBN: 3519035189
Scientific journals
- Angewandte Chemie Leading scientific journal publishing current results of chemical research
- Biophysical Journal Leading scientific journal publishing current results of biophysical research
- Cell Leading scientific journal publishing current results of biological research
- ChemBioChem Leading scientific journal publishing current results of biochemical research
- Imaging & Microscopy Leading scientific magazine covering applications and instrumentation in microscopy
- Journal of Cell Science covers the complete range of topics in cell biology, publishing current scientific result
- Langmuir An interdisciplinary journal, reporting on surfactants and self-assembly, films, biocolloids, bioelectrochemistry and more
- Microscopy & Analysis is circulated free of charge to users who specify microscopical, imaging and analytical equipment in Europe, The Americas and Asia/Pacific. Visit our website for more information.
- Nanotechnology Scientific journal publishing current results of nanotechnology research
- Nature Leading scientific magazine informing about news and trends in natural sciences research
- Nature Cell Biology Nature magazine focussing on cell biology research
- Nature Nanotechnology Nature magazine focussing on nanotechnology research
- Physik Journal Leading German physics journal informing about current results and news in physical sciences research
- PNAS Proceedings of the National Academy of Sciences
- Science Leading scientific magazine informing about news and trends in natural sciences research
Other related web sites
- Foresight Institute Organization founded to help prepare for nanotechnology and other important future technologies
- IBM Zurich Research Laboratory Interesting information about IBM research, concerning SPM and beyond
- NanoApex Nanotechnology information provider; news about current results in Nanotech research, new products and business news
- Nanodot News and discussion of coming technologies
- nanoforum.org European nanotechnology gateway; comprehensive source of information on all areas of Nanotechnology to the business, the scientific and social communities
- PUNIAS Protein Unfolding and Nano-indentation Analysis Software - might be useful
- Yahoo! Nanotechnology Link to the Nanotechnology Yahoo! category
Disclaimer: Please notice that we are not responsible for the content of the web sites to which we established links.
