Scientific papers - Atomic Force Microscopy

Cell imaging and interactions, invited review

• Pflugers Arch - Eur J Physiol 456:29-49 (2008) T. Ludwig, R. Kirmse, K. Poole, U.S. Schwarz, "Probing cellular microenvironments and tissue remodeling by atomic force microscopy "

Cells and cell structures

• J. Mol. Biol. 372(3): 594-607(2007) J. Friedrichs, A. Taubenberger, C.M. Franz, D.J. Müller, "Cellular remodelling of individual collagen fibrils visualized by time-lapse AFM"
• Exp. Dermatol. 16: 1007-1015 (2007) A. Reich, B. Lehmann, M. Meurer, D.J. Müller, "Structural alterations provoked by narrow-band ultraviolet B in immortalized keratinocytes: assessment by atomic force microscopy"
• J. Cell Sci. 118: 5315-5323 (2005) C.M. Franz, D.J. Müller "Analyzing focal adhesion structure by atomic force microscopy"
• FEBS Letters 565: 53-58 (2004) K. Poole, D. Meder, K. Simons, D. Müller, "The effect of raft lipid depletion on microvilli formation in MDCK cells, visualized by atomic force microscopy"
• FEBS Letters 579: 2001-2008 (2005) A. Sharma, K.I. Anderson, D.J. Müller, "Actin microridges characterized by laser scanning confocal and atomic force microscopy"
• J. Mol. Biol. 349: 380-386 (2005) K. Poole, K. Khairy, J. Friedrichs, C. Franz, D.A. Cisneros, J. Howard, D. Mueller, "Molecular-scale topographic cues induce the orientation and directional movement of fibroblasts on two-dimensional collagen surfaces"
• Pflugers Arch - Eur J Physiol 456:83-93 (2008) S. Wegmann, M. Miesbauer, K.F. Winklhofer, J. Tatzelt, D.J. Müller, "Observing fibrillar assemblies on scrapie-infected cells"
• Jap. J. App. Phys. 45 (3B): 2341-2344 (2006) J.M. Burns, A. Cuschieri, P.A. Campbell "Optimisation of fixation period on biological cells via time-lapse elasticity mapping"
• Nature Physics 1, 107 - 110 (2005) P. Prentice, A. Cuschieri, K. Dholakia, M. Prausnitz, P. Campbell, "Membrane disruption by optically controlled microbubble cavitation"
• Exp. Dermatol. 15: 387-391 (2006) C. Gorzelanny, T. Görge, E.-M. Schnäker, K. Thomas, T.A. Luger, S.W. Schneider, "Atomic force microscopy as an innovative tool for nanoanalysis of native stratum corneum"

Single molecules, protein, lipids

• Biophys. J. 90: 4500-4508 (2006) S. Chiantia, N. Kahya, J. Ries, P. Schwille, "Effects of ceramide on liquid-ordered domains investigated by simultaneous AFM and FCS",
• ChemPhysChem 7: 2409-2418 (2006) S. Chiantia, N. Kahya, J. Ries, P. Schwille "Combined AFM and two-focus SFCS study of raft-exhibiting model membranes"
• Langmuir 21 (14): 6317-6323 (2005) S. Chiantia, N. Kahya, P. Schwille, "Dehydration damage of domain-exhibiting supported bilayers: an AFM study on the protective effects of disaccharides and other stabilizing substances"
• Langmuir 23(14):7659-7665 (2007) S. Chiantia, N. Kahya and P. Schwille, "Raft domain reorganization driven by short- and long-chain ceramide: a combined AFM and FCS study"
• Langmuir 23: 8135-8141 (2007) M.H. Jensen, E.J. Morris, A.C. Simonsen, "Domain shapes, coarsening, and random patterns in ternary membranes",
• J. Mol. Biol. 376: 932-937 (2008) E. Canetta, S.H. Kim, N.O. Kalinina, J. Shaw, A.K. Adya, T. Gillespie, J.W.S. Brown, M. Taliansky "A plant virus movement protein forms ringlike complexes with the major nucleolar protein, fibrillarin, in vitro"
• ChemBioChem 7: 106-115 (2006) K. Kastl, M. Menke, E. L üthgens, S. Faiß, V. Gerke, A. Janshoff, C. Steinem, "Partially reversible adsorption of annexin A1 on POPC/POPS bilayers investigated by QCM measurements, SFM, and DMC simulations"
• Biochemistry 44 (46): 15296-15303 (2005) M. Menke, V. Gerke, C. Steinem "Phosphatidylserine membrane domain clustering induced by annexin A2/S100A10 heterotetramer"
• ChemBioChem 5: 1003-1006 (2004) M. Menke, M. Ross, V. Gerke, C. Steinem, "The molecular arrangement of membrane-bound annexin A2-S100A10 tetramer as revealed by scanning force microscopy"
• Langmuir 22 (18): 7454-7457 (2006) B. Windschiegl, C. Steinem, "Influence of alpha-hydroxylation of glycolipids on domain formation in lipid monolayers"
• Ultramicroscopy 106: 687-694 (2006) Z. Leonenko, E. Finot, V. Vassiliev, M. Amrein, "Effect of cholesterol on the physical properties of pulmonary surfactant films: Atomic force measurements study"
• Langmuir 22: 10135-10139 (2006) Z. Leonenko, M. Rodenstein, J. Döhner, L.M. Eng, M. Amrein, "The electrical surface potential of pulmonary surfactant"
• Biophys. J. 93: 674-683 (2007) Z. Leonenko, S. Gill, S. Baoukina, L. Monticelli, J. Doehner, L. Gunasekara, F. Felderer, M. Rodenstein, L.M. Eng, M. Amrein, "An elevated level of cholesterol impairs self-assembly of pulmonary surfactant into a functional film"
• Thrombosis and Haemostasis 97: 514-526 (2007) A. Barg, R. Ossig, T. Goerge, M. F. Schneider, H. Schiller, H. Oberleithner, S. W. Schneider, "Soluble plasma-derived von-Willebrand-factor assembles to a haemostatically active filamentous network"

Chromosome manipulation

• Nanotechnology 17: 1391-1396 (2006) K. Tsukamoto, S. Kuwazaki, K. Yamamoto, T. Ohtani, S. Sugiyama, "Dissection and high-yield recovery of nanometre-scale chromosome fragments using an atomic-force microscope"
• Jap. J. Appl. Phys. 45: 2305-2309 (2006) S. Sugiyama, T. Yoshino, K. Tsukamoto, M. Sasou, S. Kuwazaki, H. Takahashi, Y. Suetsugu, J. Narukawa, K. Yamamoto, T. Ohtani, "Application of scanning probe microscopy to genetic analysis"
• Jap. J. Appl. Phys. 45, 2337-2340 (2006) K. Tsukamoto, S. Kuwazaki, K. Yamamoto, M. Shichiri, T. Yoshino, T. Ohtani, S. Sugiyama, "Nanometer-scale dissection of chromosomes by atomic force microscopy combined with heat-denaturing treatment"

Force spectroscopy / molecular interactions

• J. Mol. Biol. 362: 925-932 (2006) A. Kedrov, C. Ziegler, D.J. Müller "Differentiating ligand and inhibitor interactions of a single antiporter"
• J. Mol. Biol. 375 (5): 1258-1266 (2008) A. Kedrov, M. Appel, H. Baumann, C. Ziegler, D.J. Müller, " Examining the dynamic energy landscape of an antiporter upon inhibitor binding"
• Biophys. J. 93: 103-112 (2007) A.J. García-Sáez, S. Chiantia, J. Salgado, P. Schwille, "Pore formation by a Bax-derived peptide: effect on the line tension of the membrane probed by AFM"
• J. Biol. Chem. 282: 33537 (2007) A.J. García-Sáez, S. Chiantia, P. Schwille, "Effect of line tension on the lateral organization of lipid membranes"
• J. Am. Chem. Soc. 129 (30): 9349-9355 (2007) Y.J. Jung, B.J. Hong, W. Zhang, S.J.B. Tendler, P.M. Williams, S. Allen and J.W. Park, "Dendron arrays for the force-based detection of DNA hybridization events"
• J. Mol. Recognit. 20: 554-560 (2007) E.Thormann, A.C Simonsen, L.K. Nielsen, O.G. Mouritsen, "Ligand-receptor interactions and membrane structure investigated by AFM and time-resolved fluorescence microscopy"
• Biochemistry 46: 12231-12237 (2007) E. Thormann, J.K. Dreyer, A.C. Simonsen, P.L. Hansen, S. Hansen, U. Holmskov, O.G. Mouritsen, "Dynamic strength of the interaction between lung surfactant protein D (SP-D) and saccharide ligands"

Polymers, nanosciences, chemistry

• Soft Matter 4: 277-285 (2008) M. Schiek, F. Balzer, K. Al-Shamery, A. Lutzenc, H.-G. Rubahn, "Light-emitting organic nanoaggregates from functionalized p-quaterphenylenes"
• Proc. SPIE 5925:31-38 (2005) F. Balzer, L. Kankate, H. Niehus, H.-G. Rubahn, "Epitaxy vs. dipole assisted growth for organic oligomer nanoaggregates"
• J. Chem. Phys. 128, 084709 (2008) L. Kankate, F. Balzer, H. Niehus, H.-G. Rubahn, "From clusters to fibers: Parameters for discontinuous para-hexaphenylene thin film growth"
• Nanotechnology 17: 984-991 (2006) F. Balzer, L. Kankate, H. Niehus, R. Frese, C. Maibohm, H.-G. Rubahn "Tailoring the growth of p-6P nanofibres using ultrathin Au layers: an organic-metal-dielectric model system"
• Proc. SPIE 6117: 20-27 (2006) F. Balzer, L. Kankate, H. Niehus, H.-G. Rubahn, "Tailoring of organic nanofiber growth for a new type of waveguides"
• J. Am. Chem. Soc. 127: 13082-13083 (2005) J.J. Davis, K.S. Coleman, K.L. Busuttil, C.B. Bagshaw, "Spatially resolved Suzuki coupling reaction initiated and controlled using a catalytic AFM probe"
• J. Am. Chem. Soc. 128 (43): 14135-14141 (2006) J.J. Davis, C.B. Bagshaw, K.L. Busuttil, Y. Hanyu, K.S. Coleman, "Spatially controlled Suzuki and Heck catalytic molecular coupling"
• Phys. Chem. Chem. Phys. 9: 2406 - 2412 (2007) M. Valtiner, S. Borodin, G. Grundmeier, "Preparation and characterisation of hydroxide stabilised ZnO(0001)-Zn-OH surfaces"
• J. Am. Chem. Soc., 130 (11): 3664 -3668 (2008) S.W. Schmidt, M.K. Beyer, H. Clausen-Schaumann, "Dynamic strength of the silicon-carbon bond observed over three decades of force-loading rates"
• J. Power Sources, 177 (1): 50-55 (2008) L. Zhou, Y.F. Cheng, M. Amrein, "Fabrication by electrolytic deposition of platinum black electrocatalyst for oxidation of ammonia in alkaline solution"
• Diamond & Related Materials 17: 66-71 (2008) W.-Y. Lee, H. Lin, L. Gu, K.-C. Leou, C.-H. Tsai, "CVD catalytic growth of single-walled carbon nanotubes with a selective diameter distribution"

Pharmacology/Drug delivery/nanoparticles

• J.Microencapsulation 23: 567-581 (2006) N. Altinbas, C. Fehmer, A. Terheiden, A. Shukla, H. Rehage, C. Mayer, "Alkylcyanoacrylate nanocapsules prepared from mini-emulsions - a comparison with the conventional approach"
• Biomacromolecules 7: 3428-38 (2006) M. Neu, J. Sitterberg, U. Bakowsky, T. Kissel, "Stabilized nanocarriers for plasmids based upon cross-linked poly(ethylene imine)"
• Pharmaceutical Research 23 (1): 184-195 (2006) S. Hariharan, V. Bhardwaj, I. Bala, J. Sitterberg, U. Bakowsky, M.N.V. Ravi Kumar "Design of estradiol loaded PLGA nanoparticulate formulations: a potential oral delivery system for hormone therapy"
• Biomacromolecules 7: 215-223 (2006) R.Y. Kannan, H.J. Salacinski, J. De Groot, I. Clatworthy, L. Bozec, M. Horton, P.E. Butler, A.M. Seifalian, "The antithrombogenic potential of a polyhedral oligomeric silsesquioxane (POSS) nanocomposite"
• Nanotechnology 18: 115710(10pp) (2007) L. Kaufner, R. Cartier, R. Wüstneck, I. Fichtner, S. Pietschmann, H. Bruhn, D. Schütt, A.F. Thünemann, U. Pison, "Poly(ethylene oxide)-block-poly(glutamic acid) coated maghemite nanoparticles: in vitro characterization and in vivo behaviour"
• Journal of Membrane Science 309: 165-174 (2008) Y. Chang, Y.J. Shih, R.C. Ruaan, A. Higuchi, W.Y. Chen, J.Y. Lai, "Preparation of poly(vinylidene fluoride) microfiltration membrane with uniform surface-copolymerized poly(ethylene glycol) methacrylate and improvement of blood compatibility"
• Nanotechnology 19: 075301 (2008) T.M. Blättler, A. Binkert, M. Zimmermann, M. Textor, J. Vörös, E. Reimhult, "From particle self-assembly to functionalized sub-micron protein patterns"
• J. Biotech. 130: 247-252 (2007) V. Saravia, S. Kupcu, M. Nolte, C. Huber, D. Pum, A. Fery, U.B. Sleytr, J.L. Toca-Herrera, "Bacterial protein patterning by micro-contact printing of PLL-g-PEG"
• Nanotechnology 18: 325102 (2007) K.-K. Liu, C.-L. Cheng, C.-C. Chang, J.-I Chao, "Biocompatible and detectable carboxylated nanodiamond on human cell"

Bionics / Biomechanics / Biotechnology

• PNAS 102 (45): 16293-16296 (2005) G. Huber, H. Mantz, R. Spolenak, K. Mecke, K. Jacobs, S.N. Gorb, E. Arzt "Evidence for capillarity contributions to gecko adhesion from single spatula nanomechanical measurements"
• Biol. Lett. 1: 2-4 (2005) G. Huber, S.N. Gorb, R. Spolenak, E. Arzt "Resolving the nanoscale adhesion of individual gecko spatulae by atomic force microscopy"
• Acta Biomaterialia 3 (4): 607-610 (2007) G. Huber, S.N. Gorb, N. Hosoda, R. Spolenak, E. Arzt, "Influence of surface roughness on gecko adhesion"
• Biophys. J. (2008) L. Kreplak, H. Herrmann, U. Aebi, "Tensile properties of single desmin intermediate filaments"
• Ultramicroscopy 105 (1-4): 79-89 (2005) L. Bozec, J. de Groot, M. Odlyha, B. Nicholls, S. Nesbitt, A. Flanagan, M. Horton "Atomic force microscopy of collagen structure in bone and dentine revealed by osteoclastic resorption"
• J Mater Sci: Mater Med 17:1043-1048 (2006) L. Bozec, M.A. Horton, "Skeletal tissues as nanomaterials"
• Biophys. J. 93:1255-1263 (2007) M.P.E. Wenger, L. Bozec, M.A. Horton, P. Mesquida, "Mechanical properties of collagen fibrils"
• Nanotechnology 19: 035506 (2008) J.F.C. Windmill, A. Zorab, D.J. Bedwell, D. Robert, "Nanomechanical and electrical characterization of a new cellular electret sensor-actuator"
• Biomaterials 29 (2): 247-256 (2008) M.S. Jaeger, K. Uhlig, H. Clausen-Schaumann, C. Duschl, "The structure and functionality of contractile forisome protein aggregates"

Cell Mechanics / Cell Motility

• Current Biology 18: 91-101 (2008) P. Kunda, A.E. Pelling, T. Liu, B. Baum, "Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis"
• J. Mol. Recognit. 20: 1-9 (2007) A.E. Pelling, F.S. Veraitch, C. Chu, B.M. Nicholls, A.L. Hemsley, C.Mason, M.A. Horton, "Mapping correlated membrane pulsations and fluctuations in human cells"
• PNAS 103: 17759-17764 (2006) Y.-B. Lu, K. Franze, G. Seifert, C. Steinhäuser, F. Kirchhoff, H. Wolburg, J. Guck, P.Janmey, E.-Q. Wei, J. Käs, A. Reichenbach, "Viscoelastic properties of individual glial cells and neurons in the CNS"
• Eur. Biophys. J. 35 (8): 713-719 (2006) C.A. Brunner, A. Ehrlicher, B. Kohlstrunk, D. Knebel, J.A. Käs, M. Goegler, "Cell migration through small gaps",
• Ultramicroscopy 107 (10):.948-953 (2007) Z. Leonenko, E. Finot, M. Amrein, "Adhesive interaction measured between AFM probe and lung epithelial type II cells"
• J.Cell. Mol. Med. 12 (2): 537-552 (2008) D. Docheva, D. Padula, C. Popov, W. Mutschler, H. Clausen-Schaumann, M. Schieker, "Researching into the cellular shape, volume and elasticity of mesenchymal stem cells, osteoblasts and osteosarcoma cells by atomic force microscopy"
• Cell Motility and the Cytoskeleton 66:193-201, 2009 Schulze C., Müller K., Käs J.A., Gerdelmann J.C., "Compaction of cell shape occurs before decrease of elasticity in CHO-K1 cells treated with actin cytoskeleton disrupting drug Cytochalasin D"

BioMAT

• App. Environ. Microbiology, 74 (2): 410-415 (2008) S. Mangold, K. Harneit, T. Rohwerder, G. Claus, W. Sand "Novel combination of atomic force microscopy and epifluorescence microscopy for visualization of leaching bacteria on pyrite"
• Hydrometallurgy in press (2008) S. Mangold, M. Laxander, K. Harneit, T. Rohwerder, G. Claus, W. Sand "Visualization of Acidithiobacillus ferrooxidans biofilms on pyrite by atomic force and epifluorescence microscopy under various experimental conditions"

TAO

• J. Raman Spectroscopy 37:311-317 (2006) A. Rasmussen, V. Deckert "Surface- and tip-enhanced Raman scattering of DNA components"
• Proc. SPIE 6093: 242-249 (2006) A. Rasmussen, C. Budich, V. Deckert, "Tip-enhanced Raman scattering (TERS) of a DNA binding compound"
• Chem Phys Chem 7(7): 1428-1430 (2006) U. Neugebauer, P. Rösch, M. Schmitt, J. Popp, C. Julien, A. Rasmussen, C. Budich, V. Deckert, "On the way to nanometer-sized information of the bacterial surface by Tip-Enhanced Raman Spectroscopy"
• Chem Phys Chem 8 (1): 124-137 (2006) U. Neugebauer, P. Rösch, M. Schmitt, J. Popp, C. Julien, A. Rasmussen, C. Budich, V. Deckert, "Towards a detailed understanding of bacterial metabolism - spectroscopic characterization of Staphylococcus Epidermis"
• Nature Nanotechnology 2, 635 - 639 (2007) M. Comellas-Aragone, H. Engelkamp, V.I. Claessen, N.A.J.M. Sommerdijk, A.E. Rowan, P.C.M. Christianen, J.C. Maan, B.J.M. Verduin, J.J.L.M. Cornelissen, R.J.M Nolte, "A virus-based single-enzyme nanoreactor"
• Biopolymers 82: 410-414 (2006) R.J. Owen, C.D. Heyes, D. Knebel, C. Röcker, G.U. Nienhaus, "An integrated instrumental setup for the combination of atomic force microscopy with optical spectroscopy"