Selected scientific papers - Cellular adhesion / cytomechanics

Technique

• Nature Protocols 5(7): 1353-1361 (2010) J. Friedrichs, J. Helenius, D.J. Mueller, "Quantifying cellular adhesion to extracellular matrix components by single-cell force spectroscopy"
• Cellular and Molecular Bioengineering 1(4): 289-300 (2008) C.M. Franz, P.-H. Puech "Atomic Force Microscopy: A Versatile Tool for Studying Cell Morphology, Adhesion and Mechanics"
• Sci. STKE 2007, pl5 (2007) C.M. Franz, A. Taubenberger, P.-H. Puech, D.J. Muller, "Studying integrin-mediated cell adhesion at the single-molecule level using AFM force spectroscopy"
• Ultramicroscopy 106: 637-644 (2006) P.-H. Puech, K. Poole, D. Knebel, D.J. Mueller "A new technical approach to quantify cell-cell adhesion forces by AFM"

Developmental biology

• PlosBiology 8 (11): e1000544 (2010) A. Diz-Muñoz, M. Krieg, M. Bergert, I. Ibarlucea-Benitez, D.J. Müller, E. Paluch, C.P. Heisenberg, "Control of Directed Cell Migration In Vivo by Membrane-to-Cortex Attachment"
• Nature Cell Biology 10(4): 429-436 (2008) M. Krieg, Y. Arboledo-Estudillo, P.H. Puech, J. Käfer, F. Graner, D.J. Mueller, C.-P. Heisenberg "Tensile forces govern germ-layer organization in Zebrafish"
• J. Cell Sci. 118: 4199-4206 (2005) P.-H. Puech, A. Taubenberger, F. Ulrich, M. Krieg, D.J. Muller, C.-P. Heisenberg "Measuring cell adhesion forces of primary gastrulating cells from zebrafish using atomic force microscopy"
• Developmental Cell 9: 555-564 (2005) F. Ulrich, M. Krieg, E.-M.Schötz, V. Link, I. Castanon, V. Schnabel, A. Taubenberger, D. Mueller, P.-H. Puech, C.-P. Heisenberg, "Wnt11 Functions in gastrulation by controlling cell cohesion through Rab5c and E-cadherin"

Cancer research

• Int. J. Cancer 128 (9): 2096–2104 (2011) S.C. Hoffmann, G. Wabnitz, Y. Samstag, G. Moldenhauer, Th. Ludwig, "Functional analysis of bispecific antibody (EpCAMxCD3)-mediated T-lymphocyte and cancer cell interaction by single-cell force spectroscopy"
• J. Immunology 186 (5): 2757-2764 (2011) S.C. Hoffmann, A. Cohnen, Th. Ludwig, C. Watzl, "2B4 Engagement Mediates Rapid LFA-1 and Actin-Dependent NK Cell Adhesion to Tumor cells as measured by Single-Cell Force Spectroscopy"
• Biochem.Biophys. Research Commun. 402 (2): 361-366 (2010) D. Docheva, D. Padula, M. Schieker, H. Clausen-Schaumann, "Effect of Collagen I and fibronectin on the adhesion, elasticity and cytoskeletal organization of prostate cancer cells"

Cell adhesion

• Cell Calcium 50 (1): 54-61 (2011) P. Steffen, A. Jung, D.B. Ngyen, T. Müller, I. Bernhardt, L. Kästner, Ch. Wagner, "Stimulation of red blood cells leads to Ca²⁺ mediated intercellular adhesion"
• The FASEB Journal 25(2), 624-631 (2011) Y.-B. Lu, I. Iandiev, M. Hollborn, N. Körber, E. Ulbricht, P. G. Hirrlinger, Th. Pannicke, Er-Q. Wei, A. Bringmann, H. Wolburg, U. Wilhelmsson, M. Pekny, P. Wiedemann, A. Reichenbach, J. A. Käs, "Reactive glial cells: increased stiffness correlates with increased intermediate filament expression"
• Nature Medicine 17: 479–487 (2011) T.K. Flach, G. Ng, A. Hari, M. Desrosiers, P. Zhang, S. Ward, M. Seamone, A. Vilaysane, A. Mucsi, Y. Fong, E. Prenner, Ch. Ling, J. Tschopp, D. Muruve, M. Amrein, Y. Shi, "Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity"
• Cytoskeleton 67: 555-563 (2010) O. Jonas, C. Duschl, "Force propagation and Force Generation in Cells"
• J.Phys: Condens. Matter 22 (19): 194101 (2010) D. Boettiger, B. Wehrle-Haller, "Integrin and glycocalyx mediated contributions to cell adhesion identified by single cell force spectroscopy"
• Biophys. J. 98 (4): 543-551 (2010) C. Selhuber-Unkel, T. Erdmann, M. Lopez-Garcia, H. Kessler, U.S. Schwarz, J. P. Spatz, "Cell Adhesion Strength is controlled by intermolecular spacing of adhesion receptors"
• Biomaterials 31 (25): 6436-6443 (2010) G. Weder, O. Guillaume-Gentil, N. Matthey, F. Montagne, H. Heizelmann, J. Vörös, "The quantification of single cell adhesion on functionalized surfaces for cell sheet engineering"
• Langmuir 26 (11): 8180-8186 (2010) G. Weder, N. Blondiaux, M. Giazzon, , N. Matthey, M. Klein, R. Pugin, H. Heinzelmann, M. Liley, "Use of Force Spectroscopy to Investigate the Adhesion of Living Adherent Cells"
• Proteomics 10: 1455-1462 (2010) J. Friedrichs, J. Helenius, D.J. Mueller, "Stimulated single-cell force spectroscopy to quantify cell adhesion receptor crosstalk"
• Biointerphases 4(2): 27-34 (2009) G. Weder, J. Vörös, M. Giazzon, N. Matthey, H. Heinzelmann, M. Liley, "Measuring cell adhesion forces during the cell cycle by force spectroscopy"
• Microscopy Research and Technique 72(12): 957-964 (2009) Veronica Saravia, José L. Toca-Herrera, "Substrate influence on cell shape and cell mechanics: HepG2 cells spread on positively charged surfaces"
• J. Cell Sci. 121: 877-886 (2008) P. Pittet, K. Lee, A.J. Kulik, J.-J. Meister, B. Hinz, "Fibrogenic fibroblasts increase intercellular adhesion strength by reinforcing individual OB-cadherin bonds"
• J. Mol. Biol. 377 (4): 1082-1093 (2008) F.A. Fierro, A. Taubenberger, P.-H. Puech, G. Ehninger, M. Bornhauser, D.J. Muller, T. Illmer, "BCR/ABL expression of myeloid progenitors increases β1-integrin mediated adhesion to stromal cells"
• Biophysical Journal 95(11): 5424-5431 (2008) Ch. Selhuber-Unkel, M. Lopez-Garcia, H. Kessler, J.P. Spatz, "Cooperativity in Adhesion Cluster Formation during Initial Cell Adhesion"
• Mol. Biol. Cell 18 (5): 1634-1644 (2007) A. Taubenberger, D.A. Cisneros, J. Friedrichs, P.-H. Puech, D.J. Muller, C.M. Franz, "Revealing early steps of {alpha}2beta1 integrin-mediated adhesion to collagen type I by using single-cell force spectroscopy"
• J. Biol. Chem. 282 (40): 29375-29383 (2007) J. Friedrichs, J.M. Torkko, J. Helenius, T.P. Teräväinen, J. Füllekrug, D.J. Müller, K. Simons, A. Manninen, "Contributions of Galectin-3 and -9 to epithelial cell adhesion analysed by single cell force spectroscopy"

Cell Mechanics / Cell Motility

• Nanomedicine: Nanotechnology, Biology and Medicine 8: 17-19 (2012) P. Eaton, V. Zuzarte-Luis, M.M. Mota, N.C. Santos, M. Prudencio, "Infection by Plasmodium changes shape and stiffness of hepatic cells"
• Development 138: 3377-3386 (2011) B. Hampoelz, Y. Azou-Gros, R. Fabre, O. Markova, P.H. Puech, Th. Lecuit, "Microtubule-induced nuclear envelope fluctuations control chromatin dynamics in Drosophila embryos"
• Nature 469: 226-231 (2011) M. P. Stewart, J. Helenius, Y. Toyoda, S.P. Ramanathan, D.J. Müller, A.A. Hyman, "Hydrostatic pressure and the actomyosin cortex drive mitotic cell rounding"
• J. Structural Biology 174 (1): 115-123 (2011) P. Traqui, A. Broisat, J. Toczek, N. Mesnier, J. Ohayon, L. Riou, "Mapping elasticity moduli of atherosclerotic plaque in situ via atomic force microscopy"
• Soft Matter 7: 3147-3154 (2011) K. Franze, M. Francke, K. Günter, A.F. Christ, N. Körber, A. Reichenbach, J. Guck, "Spatial mapping of the mechanical properties of the living retina using scanning force microscopy"
• J. Biomechanics 43 (16): 3091-3098, (2010) J. Desroches, M.A. Amrein, J.R. Maytas, "Structural and functional changes of the articular surface in a post-traumatic model of early osteoarthritis measured by atomic force microscopy"
• J. Biomechanics 43 (15): 2986-2992 (2010) A.F. Christ, K. Franze, H. Gautier, P. Moshayedi, J. Fawcett, R.J.M. Franklin, R.T. Karadottir, J. Guck, "Mechanical difference between white and gray matter in the rat cerebellum measured by scanning force microscopy"
• PNAS 107 (49): 21016-21021 (2010) A. Labernadie, C. Thibault, C. Vieu, I. Maridonneau-Parini, G.M. Charrière, "Dynamics of podosome stiffness revealed by atomic force microscopy"
• Biochemical and Biophysical Research Communications 401 (1): 143-148 (2010) A. Marg, H. Haase, T. Neumann, M. Kouno, I. Morano, "AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness "
• Cell Motility and the Cytoskeleton 66:193-201, 2009 Schulze C., Müller K., Käs J.A., Gerdelmann J.C., "Compaction of cell shape occurs before decrease of elasticity in CHO-K1 cells treated with actin cytoskeleton disrupting drug Cytochalasin D"
• Current Biology 18: 91-101 (2008) P. Kunda, A.E. Pelling, T. Liu, B. Baum, "Moesin controls cortical rigidity, cell rounding, and spindle morphogenesis during mitosis"
• J.Cell. Mol. Med. 12 (2): 537-552 (2008) D. Docheva, D. Padula, C. Popov, W. Mutschler, H. Clausen-Schaumann, M. Schieker, "Researching into the cellular shape, volume and elasticity of mesenchymal stem cells, osteoblasts and osteosarcoma cells by atomic force microscopy"
• J. Mol. Recognit. 20: 1-9 (2007) A.E. Pelling, F.S. Veraitch, C. Chu, B.M. Nicholls, A.L. Hemsley, C.Mason, M.A. Horton, "Mapping correlated membrane pulsations and fluctuations in human cells"
• Ultramicroscopy 107 (10):.948-953 (2007) Z. Leonenko, E. Finot, M. Amrein, "Adhesive interaction measured between AFM probe and lung epithelial type II cells"
• PNAS 103: 17759-17764 (2006) Y.-B. Lu, K. Franze, G. Seifert, C. Steinhäuser, F. Kirchhoff, H. Wolburg, J. Guck, P.Janmey, E.-Q. Wei, J. Käs, A. Reichenbach, "Viscoelastic properties of individual glial cells and neurons in the CNS"
• Eur. Biophys. J. 35 (8): 713-719 (2006) C.A. Brunner, A. Ehrlicher, B. Kohlstrunk, D. Knebel, J.A. Käs, M. Goegler, "Cell migration through small gaps",

Immunology

• PLoS One. 2011; 6(7): e22344 P.H. Puech, D. Nevoltris, P. Robert, L. Limozin, C. Boyer, P. Bongrand, "Force Measurements of TCR/pMHC Recognition at T Cell Surface"
• Immunology letters 136 (1): 13-20 (2011) S. Hoffmann, B.H. Hosseini, M. Hecker, I. Louban, N. Bulbuc, N. Garbi, G.H. Wabnitz, Y. Samstag, J.P. Spatz, G.J. Hämmerling, "Single cell force spectroscopy of T cells recognizing a myelin-derived peptide on antigen presenting cells"
• Arteriosclerosis, Thrombosis, and Vascular Biology 31 (2): 297-305 (2011) J. Braun, S. Hoffmann, A. Feldner, Th. Ludwig, R. Henning, M. Hecker, Th. Korff, "Endothelial Cell EphrinB2-Dependent Activation of Monocytes in Arteriosclerosis"
• PNAS 106/42 : 17852-17857 (2009) B. H. Hosseini et al., "Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy"
• Immunity 29: 1-12 (2008) G. Ng, K. Sharma, S.M. Ward, M.D. Desrosiers, L.A. Stephens, W.M. Schoel, T. Li, C.A. Lowell, C.-C. Ling, M. W. Amrein, Y. Shi, "Receptor-Independent, Direct Membrane Binding Leads to Cell-Surface Lipid Sorting and Syk Kinase Activation in Dentritic Cells"

Tether Pulling and tether characterization

• FEBS Letters 582, 3520-3524 (2008) M. Tulla, J. Helenius, J. Jokinen, , A. Taubenberger, D.J. Muller, J. Heino "TBA primes α2β1 integrins for cell adhesion"
• Angewandte Chemie 120: 9921-9923 (2008) M. Krieg, J. Helenius, C.P. Heisenberg, D.J. Müller, "A bond for a lifetime: Employing membrane nanotubes from living cells to determine receptor-ligand kinetics."
• Biophysical Journal 95: 1448-1459 (2008) J. Schmitz, M. Benoit, K.-E. Gottschalk, "The Viscoelasticity of Membrane Tethers and its Importance for Cell Adhesion."